Here's the hi-res Windows Media format E3 2005 trailer from Pathologic, the horror-adventure developed by Ice-pick Lodge and described as "a unique example of a dramatic game, which directly affects the player’s state of mind". The game will feature a town with a life of its own, which constantly changes and adequately reacts to the player's behaviour and random circumstances, three unique campaigns, several endings, a complicated system of context-sensitive music arrangement and more. Press read more to download the file.