Pop 'Em Drop 'Em Samegame features classic puzzle gameplay in which players match two or more colored blocks to clear them. As blocks are cleared, the remaining blocks will shift. If players are skilled enough, bonus points are awarded when all blocks are cleared. The game allows for play with up to four friends at home in three fast-paced multiplayer modes: Fame Game, Shame Game and Blame Game. Players can also customize the game by changing the block design and backgrounds.