Sherlock Holmes versus Jack the Ripper offers you to embody the most popular of the detectives in London in 1888. A series of particularly horrible murders takes place in this district of the East End of London where atrociously mutilated prostitutes' bodies are found. The police are unable to find a serious lead and the murders increase, creating a real psychosis. Sherlock Holmes starts looking for clues in the dark and sinister alleys of Whitechapel in order to follow the macabre trail of the one the press now calls Jack the Ripper. During a frightening adventure, Sherlock Holmes will try to bring out the true identity and the motives of the one who hides behind this scary alias.